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Treatment of experimental disseminated candidiasis with cilofungin.

Publication ,  Journal Article
Perfect, JR; Hobbs, MM; Wright, KA; Durack, DT
Published in: Antimicrob Agents Chemother
October 1989

The efficacy of cilofungin treatment of experimental disseminated candidiasis in rabbits was examined. Cilofungin treatment reduced yeast counts, especially in the kidney, with activity comparable to that of amphotericin B. The peak level of cilofungin in serum was measured at 5 min after administration of a single dose, with no drug detectable after 90 min.

Duke Scholars

Published In

Antimicrob Agents Chemother

DOI

ISSN

0066-4804

Publication Date

October 1989

Volume

33

Issue

10

Start / End Page

1811 / 1812

Location

United States

Related Subject Headings

  • Rabbits
  • Peptides, Cyclic
  • Peptides
  • Microbiology
  • Male
  • In Vitro Techniques
  • Echinocandins
  • Candidiasis
  • Animals
  • Amphotericin B
 

Citation

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Perfect, J. R., Hobbs, M. M., Wright, K. A., & Durack, D. T. (1989). Treatment of experimental disseminated candidiasis with cilofungin. Antimicrob Agents Chemother, 33(10), 1811–1812. https://doi.org/10.1128/AAC.33.10.1811
Perfect, J. R., M. M. Hobbs, K. A. Wright, and D. T. Durack. “Treatment of experimental disseminated candidiasis with cilofungin.Antimicrob Agents Chemother 33, no. 10 (October 1989): 1811–12. https://doi.org/10.1128/AAC.33.10.1811.
Perfect JR, Hobbs MM, Wright KA, Durack DT. Treatment of experimental disseminated candidiasis with cilofungin. Antimicrob Agents Chemother. 1989 Oct;33(10):1811–2.
Perfect, J. R., et al. “Treatment of experimental disseminated candidiasis with cilofungin.Antimicrob Agents Chemother, vol. 33, no. 10, Oct. 1989, pp. 1811–12. Pubmed, doi:10.1128/AAC.33.10.1811.
Perfect JR, Hobbs MM, Wright KA, Durack DT. Treatment of experimental disseminated candidiasis with cilofungin. Antimicrob Agents Chemother. 1989 Oct;33(10):1811–1812.

Published In

Antimicrob Agents Chemother

DOI

ISSN

0066-4804

Publication Date

October 1989

Volume

33

Issue

10

Start / End Page

1811 / 1812

Location

United States

Related Subject Headings

  • Rabbits
  • Peptides, Cyclic
  • Peptides
  • Microbiology
  • Male
  • In Vitro Techniques
  • Echinocandins
  • Candidiasis
  • Animals
  • Amphotericin B