Transcranial magnetic stimulation coil with electronically switchable active and sham modes.

Journal Article (Journal Article)

Blinded studies with transcranial magnetic stimulation (TMS) require a valid sham condition. A wide range of sham approaches have been implemented but they have various limitations including residual electric field in the brain, inadequate reproduction of auditory and cutaneous sensations, and/or need for electrical stimulation with scalp electrodes. We propose a quadrupole TMS coil configuration that can be electronically switched between active and sham modes. In active mode, the quadrupole coil has electric field characteristics similar to a conventional figure-8 coil. In sham mode, the quadrupole coil compared to the reverse-current sham figure-8 coil has 50% less electric field penetration depth, is 97% more focal, produces 35% less intense field in the brain, and induces scalp electric field characteristics closer to those of active TMS.

Full Text

Duke Authors

Cited Authors

  • Deng, Z-D; Peterchev, AV

Published Date

  • 2011

Published In

  • Annu Int Conf Ieee Eng Med Biol Soc

Volume / Issue

  • 2011 /

Start / End Page

  • 1993 - 1996

PubMed ID

  • 22254725

Electronic International Standard Serial Number (EISSN)

  • 2694-0604

Digital Object Identifier (DOI)

  • 10.1109/IEMBS.2011.6090561


  • eng

Conference Location

  • United States