Assessing the current role of platelet function testing.


Journal Article (Review)

In vitro platelet function tests are commonly applied in research and offer justification for using antiplatelet therapy. However, studies assessing the ability of standardized platelet function tests to predict patients' clinical response to aspirin or clopidogrel have generated contradictory results. At this time, there is no standardized definition for resistance to antiplatelet therapy, and the appropriate treatment of patients who are hyporesponsive to these agents is not known. Although such tests have a role in research, their place in guiding therapy remains to be established, and prospective trials are urgently needed. The ideal platelet function test for clinical practice would be rapid, easy-to-use, inexpensive, and reliable.

Full Text

Duke Authors

Cited Authors

  • Braunwald, E; Angiolillo, D; Bates, E; Berger, PB; Bhatt, D; Cannon, CP; Furman, MI; Gurbel, P; Michelson, AD; Peterson, E; Wiviott, S

Published Date

  • March 2008

Published In

Volume / Issue

  • 31 / 3 Suppl 1

Start / End Page

  • I10 - I16

PubMed ID

  • 18481816

Pubmed Central ID

  • 18481816

Electronic International Standard Serial Number (EISSN)

  • 1932-8737

International Standard Serial Number (ISSN)

  • 0160-9289

Digital Object Identifier (DOI)

  • 10.1002/clc.20361


  • eng