Context dependence of meiotic recombination hotspots in yeast: the relationship between recombination activity of a reporter construct and base composition.

Journal Article (Journal Article)

Borde and colleagues reported that a reporter plasmid inserted at different genomic locations in Saccharomyces cerevisiae had different levels of meiotic recombination activity. We show that the level of recombination activity is very significantly correlated with the GC content of DNA sequences flanking the insertion.

Full Text

Duke Authors

Cited Authors

  • Petes, TD; Merker, JD

Published Date

  • December 2002

Published In

Volume / Issue

  • 162 / 4

Start / End Page

  • 2049 - 2052

PubMed ID

  • 12524370

Pubmed Central ID

  • PMC1462354

International Standard Serial Number (ISSN)

  • 0016-6731

Digital Object Identifier (DOI)

  • 10.1093/genetics/162.4.2049


  • eng

Conference Location

  • United States