Meiotic recombination hot spots and cold spots.
Journal Article (Journal Article;Review)
Meiotic recombination events are distributed unevenly throughout eukaryotic genomes. This inhomogeneity leads to distortions of genetic maps that can hinder the ability of geneticists to identify genes by map-based techniques. Various lines of evidence, particularly from studies of yeast, indicate that the distribution of recombination events might reflect, at least in part, global features of chromosome structure, such as the distribution of modified nucleosomes.
Full Text
Duke Authors
Cited Authors
- Petes, TD
Published Date
- May 2001
Published In
Volume / Issue
- 2 / 5
Start / End Page
- 360 - 369
PubMed ID
- 11331902
International Standard Serial Number (ISSN)
- 1471-0056
Digital Object Identifier (DOI)
- 10.1038/35072078
Language
- eng
Conference Location
- England