Measurements of excision repair tracts formed during meiotic recombination in Saccharomyces cerevisiae.

Journal Article (Journal Article)

During meiotic recombination in the yeast Saccharomyces cerevisiae, heteroduplexes are formed at a high frequency between HIS4 genes located on homologous chromosomes. Using mutant alleles of the HIS4 gene that result in poorly repaired mismatches in heteroduplex DNA, we find that heteroduplexes often span a distance of 1.8 kb. In addition, we show that about one-third of the repair tracts initiated at well-repaired mismatches extend 900 bp.

Full Text

Duke Authors

Cited Authors

  • Detloff, P; Petes, TD

Published Date

  • April 1992

Published In

Volume / Issue

  • 12 / 4

Start / End Page

  • 1805 - 1814

PubMed ID

  • 1549127

Pubmed Central ID

  • PMC369624

International Standard Serial Number (ISSN)

  • 0270-7306

Digital Object Identifier (DOI)

  • 10.1128/mcb.12.4.1805-1814.1992

Language

  • eng

Conference Location

  • United States