High-frequency meiotic gene conversion between repeated genes on nonhomologous chromosomes in yeast.

Journal Article (Journal Article)

We have used a genetic system that allows detection of meiotic recombination events between repeated sequences on nonhomologous chromosomes in the yeast Saccharomyces cerevisiae. We have found that recombination between these sequences occurs at a frequency of about 0.5%, and the events observed were nonreciprocal (gene conversions). Surprisingly, the frequency of conversion between the repeated genes on nonhomologous chromosomes observed in this study is similar to that observed between allelic genes. This result is discussed in connection with the role of the synaptonemal complex in meiotic recombination and with the relationship between reciprocal and nonreciprocal recombination.

Full Text

Duke Authors

Cited Authors

  • Jinks-Robertson, S; Petes, TD

Published Date

  • May 1, 1985

Published In

Volume / Issue

  • 82 / 10

Start / End Page

  • 3350 - 3354

PubMed ID

  • 3889906

Pubmed Central ID

  • PMC397773

International Standard Serial Number (ISSN)

  • 0027-8424

Digital Object Identifier (DOI)

  • 10.1073/pnas.82.10.3350


  • eng

Conference Location

  • United States