Replicating circular DNA molecules in yeast.

Journal Article (Journal Article)

The yeast Saccharomyces cerevisiae contains a class of small circular DNA molecules, approximately 2 mum in contour length (Sinclair et al., 1967). In this report, it is shown that these molecules replicate as double-branched circles, similar to those observed during replication of the bacteriophage lambda and Escherichia coli chromosomes. A normal rate of replication of these DNA circles requires the function of a nuclear gene, cdc 8.

Full Text

Duke Authors

Cited Authors

  • Petes, TD; Williamson, DH

Published Date

  • March 1, 1975

Published In

Volume / Issue

  • 4 / 3

Start / End Page

  • 249 - 253

PubMed ID

  • 1091361

International Standard Serial Number (ISSN)

  • 0092-8674

Digital Object Identifier (DOI)

  • 10.1016/0092-8674(75)90172-5


  • eng

Conference Location

  • United States