Replicating circular DNA molecules in yeast.
Journal Article (Journal Article)
The yeast Saccharomyces cerevisiae contains a class of small circular DNA molecules, approximately 2 mum in contour length (Sinclair et al., 1967). In this report, it is shown that these molecules replicate as double-branched circles, similar to those observed during replication of the bacteriophage lambda and Escherichia coli chromosomes. A normal rate of replication of these DNA circles requires the function of a nuclear gene, cdc 8.
- Petes, TD; Williamson, DH
- March 1, 1975
Volume / Issue
- 4 / 3
Start / End Page
- 249 - 253
International Standard Serial Number (ISSN)
Digital Object Identifier (DOI)
- United States