Renal stones
Conservative and selective medical therapy of nephrolithiasis is highly effective in preventing new stone formation. An overall remission rate of greater than 80% and an overall reduction in individual stone formation rate of greater than 90% can be obtained in patients with nephrolithiasis. In patients with mild-to-moderate stone disease, virtually total control can be achieved, with a remission rate of greater than 95%. Selective pharmacologic therapy of nephrolithiasis also offers the advantages of overcoming nonrenal complications as well as averting certain side effects that may be caused by nonselective medical therapy. Despite these advantages, it is clear that selective medical therapy does not provide total control of stone disease in all patients. A satisfactory response requires continued, dedicated compliance by patients to the recommended program and a commitment of the physician to provide long-term follow-up and care.
