Management of gynecologic surgery in the patient with factor XI deficiency: a review of the literature.

Journal Article (Journal Article;Review)

UNLABELLED: Factor XI deficiency is a rare bleeding disorder that is more commonly found in Ashkenazi Jews. Bleeding manifestations of this disorder are varied and poorly correlate with factor XI levels. Spontaneous bleeding is uncommon, whereas delayed postoperative bleeding is often the presentation of factor XI deficiency. To date, there are no standard recommendations for prophylactic treatment in women undergoing gynecologic surgery. Here, we review published cases of gynecological surgery in women with factor XI deficiency and discuss the risks and benefits of various therapeutic options. TARGET AUDIENCE: Obstetricians And Gynecologists. LEARNING OBJECTIVES: After participating in this activity, physicians should be better able to identify the pathophysiology of factor XI deficiency. Compare previous outcomes of prophylactic treatment in patients with factor XI deficiency undergoing gynecological surgery. Implement possible prophylactic therapies for patients with factor XI deficiency undergoing gynecological surgery.

Full Text

Duke Authors

Cited Authors

  • Steward, RG; Saleh, OA; James, AH; Shah, AA; Price, TM

Published Date

  • May 2012

Published In

Volume / Issue

  • 67 / 5

Start / End Page

  • 291 - 297

PubMed ID

  • 22624777

Electronic International Standard Serial Number (EISSN)

  • 1533-9866

Digital Object Identifier (DOI)

  • 10.1097/OGX.0b013e3182524da0


  • eng

Conference Location

  • United States