A unique case of unilateral synophthalmia.

Journal Article (Journal Article)

Developmental anomalies resulting in a single eye (cyclopia) or fusion of the eyes (synophthalmia) are rare. Examples of unilateral synophthalmia-in which there are 1 normal and 2 fused eyes from 3 anlagen in 2 orbits, 1 lateral proboscis, and 3 optic nerves-are even more rare. Herein, I report a unique fetus with unilateral synophthalmia that was not associated with a lateral proboscis but instead had an extra cerebral hemisphere. I postulate that the unilateral synophthalmia, accessory cerebral hemisphere, and minor structural abnormalities in the skull base were the result of failure in separating a monozygous twin, a situation similar to that postulated as the cause of fetus in fetu.

Full Text

Duke Authors

Cited Authors

  • Proia, AD

Published Date

  • March 2011

Published In

Volume / Issue

  • 14 / 2

Start / End Page

  • 130 - 133

PubMed ID

  • 20528261

International Standard Serial Number (ISSN)

  • 1093-5266

Digital Object Identifier (DOI)

  • 10.2350/10-03-0809-CR.1


  • eng

Conference Location

  • United States