Large-cell lymphoma presenting with a distinctive inflammatory dermatosis


Journal Article

Severe, progressively enlarging inflammatory plaques of the upper trunk and neck developed in a 12-year-old girl. Histologic examination revealed a unique inflammatory cell infiltrate that consisted of chronic inflammation in the dermis subtending spongiosis with a diffuse neutrophilic epidermal infiltrate. A tumor in the right axilla was found by computed tomography. Tissue obtained at open biopsy examination demonstrated a large-cell lymphoma of B-cell origin. The tumor and dermatosis responded dramatically to chemotherapy. The distinctive histologic pattern and clinical course suggest that this dermatosis may represent an unusual paraneoplastic presentation of large-cell lymphoma. © 1991, American Academy of Dermatology, Inc.. All rights reserved.

Full Text

Duke Authors

Cited Authors

  • Tope, WD; Fishbein, JD; White, PF; Prose, NS

Published Date

  • January 1, 1991

Published In

Volume / Issue

  • 25 / 5

Start / End Page

  • 912 - 915

International Standard Serial Number (ISSN)

  • 0190-9622

Digital Object Identifier (DOI)

  • 10.1016/0190-9622(91)70282-7

Citation Source

  • Scopus