Cutaneous granulomas in children with combined immunodeficiency


Journal Article

Noninfectious cutaneous granulomas, particularly in an acral distribution, may be an early sign of mixed cellular and humoral immunodeficiency. Special stains of skin biopsy sections and cultures for bacteria, acid-fast bacilli, and fungi are important in eliminating the possibility of underlying pathogens. In three children with combined immunodeficiency and cutaneous granulomas, the administration of moderate- to high-dose systemic corticosteroids was the most effective therapy. However, careful consideration should be given before administering systemic corticosteroids to an immunocompromised patient. © 1991, American Academy of Dermatology, Inc.. All rights reserved.

Full Text

Duke Authors

Cited Authors

  • Siegfried, EC; Prose, NS; Friedman, NJ; Paller, AS

Published Date

  • January 1, 1991

Published In

Volume / Issue

  • 25 / 5

Start / End Page

  • 761 - 766

International Standard Serial Number (ISSN)

  • 0190-9622

Digital Object Identifier (DOI)

  • 10.1016/S0190-9622(08)80965-6

Citation Source

  • Scopus