The laboratory diagnosis of Lyme disease.

Journal Article (Journal Article;Review)

Growing awareness of Lyme disease, caused by the tickborne spirochete Borrelia burgdorferi has led to a marked increase in laboratory procedures to help in its diagnosis. Despite the frequent ordering of serologic tests specific for Lyme disease, there remains confusion in the accurate interpretation of these tests. Because of the important cutaneous manifestations of B burgdorferi infection, dermatologists should understand the role of the laboratory in Borrelia-related conditions. This article reviews laboratory techniques available for the diagnosis of Lyme disease. The role of histologic findings and culture, the sensitivity, specificity, and reproducibility of commonly used serologic tests, the effects of disease duration and treatment on serologic results, and the future of laboratory diagnosis are described.

Full Text

Duke Authors

Cited Authors

  • Berg, D; Abson, KG; Prose, NS

Published Date

  • June 1991

Published In

Volume / Issue

  • 127 / 6

Start / End Page

  • 866 - 870

PubMed ID

  • 2036035

International Standard Serial Number (ISSN)

  • 0003-987X


  • eng

Conference Location

  • United States