zeta-Crystallin is a major protein in the lens of Camelus dromedarius.

Published

Journal Article

Camel (Camelus dromedarius) lenses contain a protein with an apparent subunit Mr 38,000 that constitutes approximately 8-13% of the total protein. The protein has been purified and has a native Mr 140,000 as determined by gel filtration. This is consistent with its being a tetramer. The protein reacts with antibodies raised against both guinea pig zeta-crystallin and peptides corresponding to amino acids 1-10 and 295-308, but not to antibodies raised against amino acids 320-328 of zeta-crystallin. Based on these criteria it is concluded that this protein, which is a major constituent of camel lens, is zeta-crystallin. This may be the first example of a protein (enzyme) being independently utilized as a crystallin in the lens of species from two mammalian orders.

Full Text

Duke Authors

Cited Authors

  • Garland, D; Rao, PV; Del Corso, A; Mura, U; Zigler, JS

Published Date

  • February 15, 1991

Published In

Volume / Issue

  • 285 / 1

Start / End Page

  • 134 - 136

PubMed ID

  • 1990971

Pubmed Central ID

  • 1990971

International Standard Serial Number (ISSN)

  • 0003-9861

Digital Object Identifier (DOI)

  • 10.1016/0003-9861(91)90339-k

Language

  • eng

Conference Location

  • United States