Bleeding and the use of antiplatelet agents in the management of acute coronary syndromes and atrial fibrillation.

Journal Article (Review)

Antiplatelet therapy serves an important role in the management of acute coronary syndromes and in reducing the risk of thrombotic complications from atrial fibrillation. There has been rapid development of newer and more potent antiplatelet therapies over the last several years that have further reduced ischemic complications, but with a trade-off of increased bleeding risk. Bleeding complications associated with antiplatelet and anticoagulant therapies are associated with significantly increased risk of adverse outcomes, including death. Understanding the risk of bleeding associated with antiplatelet agents is critical to developing strategies to mitigate this risk.

Full Text

Duke Authors

Cited Authors

  • Vavalle, JP; Rao, SV

Published Date

  • January 2012

Published In

Volume / Issue

  • 47 /

Start / End Page

  • 125 - 140

PubMed ID

  • 22906908

Pubmed Central ID

  • 22906908

Electronic International Standard Serial Number (EISSN)

  • 1662-2839

International Standard Serial Number (ISSN)

  • 0065-2326

Digital Object Identifier (DOI)

  • 10.1159/000338072


  • eng