Evolution and sequence analysis of a human Y-chromosomal DNA fragment.


Journal Article

A Y-chromosomal DNA fragment has been isolated from a human Y-Charon 21A recombinant library. Evolutionary analysis of 1F5 indicates that the size and sequence of this fragment have been conserved in higher primates. Deletion mapping and in situ hybridization analysis have localized 1F5 to the middle euchromatic portion of the long arm of the human Y chromosome at Yq11.2. Sequence analysis revealed the presence of an atypical Alu element and two regions rich in polypyrimidine-polypurine residues.

Full Text

Cited Authors

  • Whisenant, EC; Rasheed, BK; Ostrer, H; Bhatnagar, YM

Published Date

  • August 1991

Published In

Volume / Issue

  • 33 / 2

Start / End Page

  • 133 - 141

PubMed ID

  • 1920449

Pubmed Central ID

  • 1920449

Electronic International Standard Serial Number (EISSN)

  • 1432-1432

International Standard Serial Number (ISSN)

  • 0022-2844

Digital Object Identifier (DOI)

  • 10.1007/bf02193627


  • eng