Methed-up FOXOs can't in-Akt-ivate.

Journal Article (Journal Article)

In this issue of Molecular Cell, Yamagata et al. (2008) identify a role for the protein methyltransferase, PRMT1, in Akt-dependent regulation of the FOXO1 transcription factor and demonstrate another level of control in this critical metabolic and cell survival signaling pathway.

Full Text

Duke Authors

Cited Authors

  • Michalek, RD; Rathmell, JC

Published Date

  • October 24, 2008

Published In

Volume / Issue

  • 32 / 2

Start / End Page

  • 160 - 162

PubMed ID

  • 18951081

Pubmed Central ID

  • PMC2603568

Electronic International Standard Serial Number (EISSN)

  • 1097-4164

Digital Object Identifier (DOI)

  • 10.1016/j.molcel.2008.10.006

Language

  • eng

Conference Location

  • United States