Immunosuppressive protocols and immunological challenges related to hand transplantation.

Journal Article (Review)

There are many immunological challenges related to hand transplantation. Curbing the immune system's ability to effectively mount an immune response against the graft is the goal. As the various components of the immune response are defined and their mechanisms of action delineated, more specific immunosuppressive agents and protocols have been developed. Complications related to immunosuppression in hand transplant recipients are similar to incidences among solid organ recipients. With longer follow-up, the increased cardiovascular risk factors or the development of a neoplasm will likely cause mortality. Standardizing immunosuppression in hand transplantation with the long-term goal of minimization is critically needed.

Full Text

Duke Authors

Cited Authors

  • Ravindra, KV; Ildstad, ST

Published Date

  • November 2011

Published In

Volume / Issue

  • 27 / 4

Start / End Page

  • 467 - ix

PubMed ID

  • 22051388

Electronic International Standard Serial Number (EISSN)

  • 1558-1969

Digital Object Identifier (DOI)

  • 10.1016/j.hcl.2011.07.001

Language

  • eng

Conference Location

  • United States