West Nile virus-associated encephalitis in recipients of renal and pancreas transplants: case series and literature review.

Journal Article (Journal Article;Review)

Although West Nile fever is mild in the vast majority of infected persons, there is growing evidence that the disease may be more severe in the immunocompromised population. We describe 3 recipients of kidney or pancreas transplants who developed West Nile fever, 2 of whom had meningoencephalitis. As is the norm when treating serious infections in transplant recipients, a reduction of immunosuppression was pursued for these patients. Despite the severe nature of the disease in 2 patients, all recovered from the disease. The time course of neurologic recovery in the 2 patients with meningoencephalitis is highlighted. We also review the literature on West Nile fever in organ transplant recipients. In areas where West Nile virus is endemic, one must have a high index of suspicion for the illness when dealing with fever in transplant recipients.

Full Text

Duke Authors

Cited Authors

  • Ravindra, KV; Freifeld, AG; Kalil, AC; Mercer, DF; Grant, WJ; Botha, JF; Wrenshall, LE; Stevens, RB

Published Date

  • May 1, 2004

Published In

Volume / Issue

  • 38 / 9

Start / End Page

  • 1257 - 1260

PubMed ID

  • 15127337

Electronic International Standard Serial Number (EISSN)

  • 1537-6591

Digital Object Identifier (DOI)

  • 10.1086/383325


  • eng

Conference Location

  • United States