A model for fast axonal transport.

Journal Article (Journal Article)

A model for fast axonal transport is developed in which the essential features are that organelles may interact with mechanochemical cross-bridges that in turn interact with microtubules, forming an organelle-engine-microtubule complex which is transported along the microtubules. Computer analysis of the equations derived to describe such a system show that most of the experimental observations on fast axonal transport can be simulated by the model, indicating that the model is useful for the interpretation and design of experiments aimed at clarifying the mechanism of fast axonal transport.

Full Text

Duke Authors

Cited Authors

  • Blum, JJ; Reed, MC

Published Date

  • January 1, 1985

Published In

Volume / Issue

  • 5 / 6

Start / End Page

  • 507 - 527

PubMed ID

  • 2416456

International Standard Serial Number (ISSN)

  • 0271-6585

Digital Object Identifier (DOI)

  • 10.1002/cm.970050607


  • eng