Remote sensing of protein adsorption using a single optical fiber

Journal Article (Journal Article)

Fluorescence from dye-labeled protein adsorbed at a solid-liquid interface was monitored with a remote interfacial chemical sensor utilizing a single optical fiber. Evanescently excited and collected fluorescence obtained using the sensor showed that adsorption of protein onto the fiber core sensing surface from a flowing solution was detected. The results demonstrate that protein adsorption can be remotely detected and monitored with time. It is anticipated that this approach will be extended to the sensing of specific surface adsorbed molecules. © 1986.

Full Text

Duke Authors

Cited Authors

  • Newby, K; Andrade, JD; Benner, RE; Reichert, WM

Published Date

  • January 1, 1986

Published In

Volume / Issue

  • 111 / 1

Start / End Page

  • 280 - 282

International Standard Serial Number (ISSN)

  • 0021-9797

Digital Object Identifier (DOI)

  • 10.1016/0021-9797(86)90028-7

Citation Source

  • Scopus