A framework for modeling DNA based molecular systems
Recent successes in building large scale DNA nanostructures and in constructing DNA nanomechanical devices have inspired scientists to design more complex nanoscale systems. The design process can be made considerably more efficient and robust with the help of simulators that can model such systems accurately prior to their experimental implementation. In this paper, we propose a framework for a discrete event simulator for simulating the DNA based nanorobotical systems. It has two major components: a physical model and a kinetic model. The physical model captures the conformational changes of molecules, molecular motions and molecular collisions. The kinetic model governs the modeling of various chemical reactions in a DNA nanorobotical systems including the hybridization, dehybridization and strand displacement. The feasibility of such a framework is demonstrated by some preliminary implementations. Copyright © 2008 American Scientific Publishers All rights reserved.
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Related Subject Headings
- Nanoscience & Nanotechnology
- 1007 Nanotechnology
- 0913 Mechanical Engineering
- 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics
Citation
Published In
DOI
ISSN
Publication Date
Volume
Issue
Start / End Page
Related Subject Headings
- Nanoscience & Nanotechnology
- 1007 Nanotechnology
- 0913 Mechanical Engineering
- 0202 Atomic, Molecular, Nuclear, Particle and Plasma Physics