Programmable DNA self-assemblies for nanoscale organization of ligands and proteins.


Journal Article

We demonstrate the precise control of periodic spacing between individual protein molecules by programming the self-assembly of DNA tile templates. In particular, we report the application of two self-assembled periodic DNA structures, two-dimensional nanogrids, and one-dimensional nanotrack, as template for programmable self-assembly of streptavidin protein arrays with controlled density.

Full Text

Duke Authors

Cited Authors

  • Park, SH; Yin, P; Liu, Y; Reif, JH; LaBean, TH; Yan, H

Published Date

  • April 2005

Published In

Volume / Issue

  • 5 / 4

Start / End Page

  • 729 - 733

PubMed ID

  • 15826117

Pubmed Central ID

  • 15826117

Electronic International Standard Serial Number (EISSN)

  • 1530-6992

International Standard Serial Number (ISSN)

  • 1530-6984

Digital Object Identifier (DOI)

  • 10.1021/nl050175c


  • eng