United States geographic bacteria susceptibility patterns

Journal Article

Antimicrobial drug resistance in bacterial pathogens continues, with 1997 seeing reports of Staphylococcus aureus no longer fully susceptible to vancomycin occurring in the United States. To better deal with this rapidly developing problem, we present the third year of United States national data that high-lights the geographic nature of increasing resistance to antimicrobial agents. In 1997, we observed increasing numbers of vancomycin-resistant Enterococcus faecium, more methicillin-resistant Staphylococcus aureus (MRSA), and an apparent spreading of penicillin resistance in pneumococci. The majority of reporting sites now indicates that over 20% of Pseudomonas aeruginosa are fully resistant to ciprofloxacin, the only oral agent available for treating this pathogen. With increasing resistance coming at a time of decreasing available resources, it is more clear than ever before that the future of infectious diseases and clinical microbiology remains filled with challenge. (C) 1999 Elsevier Science Inc.

Full Text

Duke Authors

Cited Authors

  • Munro, S; Baron, EJ; Robinson, A; Walsh, P; Meier, FA; Hacek, DM; Peterson, LR; Reynolds, JK; Allen, SD; III, FC; Pfaller, MA; Jones, RN; Gilligan, PH; Wait, K; Harrell, LJ; Reller, LB; Hall, G; Mann, LM; Woods, GI; Carroll, KC

Published Date

  • 1999

Published In

Volume / Issue

  • 35 / 2

Start / End Page

  • 143 - 151

PubMed ID

  • 10579095

International Standard Serial Number (ISSN)

  • 0732-8893

Digital Object Identifier (DOI)

  • 10.1016/S0732-8893(99)00067-X