Interpretive criteria and quality control for antimicrobial susceptibility tests of levofloxacin.

Published

Journal Article

To confirm preliminary interpretive breakpoints for prototype 5 micrograms levofloxacin disks, 490 strains were tested in vitro using commercially manufactured disks. For in vitro susceptibility testing, 5 micrograms levofloxacin disks can be used with interpretive criteria of < or = 12 mm for resistant (MIC > or = 8.0 micrograms/ml) and > or = 16 mm for susceptible (MIC < or = 2.0 micrograms/ml). Proposed quality control limits for tests of levofloxacin are as follows: Escherichia coli ATCC 25922, zones 29-37 mm or MIC 0.008-0.03 microgram/ml; Pseudomonas aeruginosa ATCC 27853, zones 19-26 mm or MIC 0.5-2.0 micrograms/ml; Staphylococcus aureus ATCC 25923, zones 24-31 mm; Staphylococcus aureus ATCC 29213, MIC 0.06-0.25 microgram/ml and Enterococcus faecalis ATCC 29212, MIC 0.25-2.0 micrograms/ml.

Full Text

Duke Authors

Cited Authors

  • Barry, A; Fuchs, P; Tenover, F; Allen, S; Hardy, D; Jorgensen, J; McLaughlin, J; Reller, L

Published Date

  • October 1994

Published In

Volume / Issue

  • 13 / 10

Start / End Page

  • 822 - 826

PubMed ID

  • 7889952

Pubmed Central ID

  • 7889952

Electronic International Standard Serial Number (EISSN)

  • 1435-4373

International Standard Serial Number (ISSN)

  • 0934-9723

Digital Object Identifier (DOI)

  • 10.1007/bf02111343

Language

  • eng