Distribution of opioid peptide gene expression in the limbic system of Fawn-Hooded (alcohol-preferring) and Wistar-Kyoto (alcohol-non-preferring) rats.
Publication
, Journal Article
Cowen, MS; Rezvani, A; Jarrott, B; Lawrence, AJ
Published in: Brain Res
June 15, 1998
Preprodynorphin and preproenkephalin mRNA expression was examined in the CNS of two rat strains, the alcohol-preferring Fawn-Hooded (FH) and the alcohol-non-preferring Wistar-Kyoto (WKY), using in situ hybridisation histochemistry. Relative to the WKY, the FH showed significantly lower levels of preproenkephalin mRNA in the striatum and nucleus accumbens (-24% and -17% respectively), but a higher level of preprodynorphin mRNA in the hippocampus (+33%). The depressed level of preproenkephalin mRNA in the nucleus accumbens may be implicated in alcohol-seeking behaviour.
Duke Scholars
Published In
Brain Res
DOI
ISSN
0006-8993
Publication Date
June 15, 1998
Volume
796
Issue
1-2
Start / End Page
323 / 326
Location
Netherlands
Related Subject Headings
- Tissue Distribution
- Rats, Inbred WKY
- Rats, Inbred Strains
- Rats
- RNA, Messenger
- Protein Precursors
- Neurology & Neurosurgery
- Limbic System
- In Situ Hybridization
- Histocytochemistry
Citation
APA
Chicago
ICMJE
MLA
NLM
Cowen, M. S., Rezvani, A., Jarrott, B., & Lawrence, A. J. (1998). Distribution of opioid peptide gene expression in the limbic system of Fawn-Hooded (alcohol-preferring) and Wistar-Kyoto (alcohol-non-preferring) rats. Brain Res, 796(1–2), 323–326. https://doi.org/10.1016/s0006-8993(98)00432-6
Cowen, M. S., A. Rezvani, B. Jarrott, and A. J. Lawrence. “Distribution of opioid peptide gene expression in the limbic system of Fawn-Hooded (alcohol-preferring) and Wistar-Kyoto (alcohol-non-preferring) rats.” Brain Res 796, no. 1–2 (June 15, 1998): 323–26. https://doi.org/10.1016/s0006-8993(98)00432-6.
Cowen MS, Rezvani A, Jarrott B, Lawrence AJ. Distribution of opioid peptide gene expression in the limbic system of Fawn-Hooded (alcohol-preferring) and Wistar-Kyoto (alcohol-non-preferring) rats. Brain Res. 1998 Jun 15;796(1–2):323–6.
Cowen, M. S., et al. “Distribution of opioid peptide gene expression in the limbic system of Fawn-Hooded (alcohol-preferring) and Wistar-Kyoto (alcohol-non-preferring) rats.” Brain Res, vol. 796, no. 1–2, June 1998, pp. 323–26. Pubmed, doi:10.1016/s0006-8993(98)00432-6.
Cowen MS, Rezvani A, Jarrott B, Lawrence AJ. Distribution of opioid peptide gene expression in the limbic system of Fawn-Hooded (alcohol-preferring) and Wistar-Kyoto (alcohol-non-preferring) rats. Brain Res. 1998 Jun 15;796(1–2):323–326.
Published In
Brain Res
DOI
ISSN
0006-8993
Publication Date
June 15, 1998
Volume
796
Issue
1-2
Start / End Page
323 / 326
Location
Netherlands
Related Subject Headings
- Tissue Distribution
- Rats, Inbred WKY
- Rats, Inbred Strains
- Rats
- RNA, Messenger
- Protein Precursors
- Neurology & Neurosurgery
- Limbic System
- In Situ Hybridization
- Histocytochemistry