Cytotoxic, antifouling bromotyramines: a synthetic study on simple marine natural products and Their analogues.
Journal Article (Journal Article)
Synthesis and biological evaluation of two naturally-occurring bromotyramines, moloka'iamine 1 and 3,5-dibromo-4-methoxy-beta-phenethylamine 2, together with several analogues, have been completed. Bromotyramine 2 is cytotoxic, and was found to be a potent antifoulant. Analogues 15 and 16 also displayed significant cytotoxic and antifouling activities.
Full Text
Duke Authors
Cited Authors
- Schoenfeld, RC; Conova, S; Rittschof, D; Ganem, B
Published Date
- March 2002
Published In
Volume / Issue
- 12 / 5
Start / End Page
- 823 - 825
PubMed ID
- 11859011
Electronic International Standard Serial Number (EISSN)
- 1464-3405
International Standard Serial Number (ISSN)
- 0960-894X
Digital Object Identifier (DOI)
- 10.1016/s0960-894x(02)00022-7
Language
- eng