Cytotoxic, antifouling bromotyramines: a synthetic study on simple marine natural products and Their analogues.

Journal Article

Synthesis and biological evaluation of two naturally-occurring bromotyramines, moloka'iamine 1 and 3,5-dibromo-4-methoxy-beta-phenethylamine 2, together with several analogues, have been completed. Bromotyramine 2 is cytotoxic, and was found to be a potent antifoulant. Analogues 15 and 16 also displayed significant cytotoxic and antifouling activities.

Full Text

Duke Authors

Cited Authors

  • Schoenfeld, RC; Conova, S; Rittschof, D; Ganem, B

Published Date

  • March 11, 2002

Published In

Volume / Issue

  • 12 / 5

Start / End Page

  • 823 - 825

PubMed ID

  • 11859011

International Standard Serial Number (ISSN)

  • 0960-894X

Language

  • eng

Conference Location

  • England