Nucleotide sequence of the LYS2 gene of Saccharomyces cerevisiae: homology to Bacillus brevis tyrocidine synthetase 1.

Journal Article (Journal Article)

The Saccharomyces cerevisiae LYS2 gene, which encodes alpha-aminoadipate reductase, an essential enzyme in the yeast lysine biosynthetic pathway, has been sequenced. A large open reading frame (ORF) has been identified which can specify a 1392-amino acid protein with a deduced Mr of 155,344. A DNA database search using the translated LYS2 ORF as a probe has revealed significant aa sequence homology to the Bacillus brevis enzyme tyrocidine synthetase 1.

Full Text

Duke Authors

Cited Authors

  • Morris, ME; Jinks-Robertson, S

Published Date

  • February 1, 1991

Published In

Volume / Issue

  • 98 / 1

Start / End Page

  • 141 - 145

PubMed ID

  • 2013406

International Standard Serial Number (ISSN)

  • 0378-1119

Digital Object Identifier (DOI)

  • 10.1016/0378-1119(91)90117-t


  • eng

Conference Location

  • Netherlands