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Nucleotide sequence of the LYS2 gene of Saccharomyces cerevisiae: homology to Bacillus brevis tyrocidine synthetase 1.

Publication ,  Journal Article
Morris, ME; Jinks-Robertson, S
Published in: Gene
February 1, 1991

The Saccharomyces cerevisiae LYS2 gene, which encodes alpha-aminoadipate reductase, an essential enzyme in the yeast lysine biosynthetic pathway, has been sequenced. A large open reading frame (ORF) has been identified which can specify a 1392-amino acid protein with a deduced Mr of 155,344. A DNA database search using the translated LYS2 ORF as a probe has revealed significant aa sequence homology to the Bacillus brevis enzyme tyrocidine synthetase 1.

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Published In

Gene

DOI

ISSN

0378-1119

Publication Date

February 1, 1991

Volume

98

Issue

1

Start / End Page

141 / 145

Location

Netherlands

Related Subject Headings

  • Sequence Homology, Nucleic Acid
  • Saccharomyces cerevisiae
  • Restriction Mapping
  • Peptide Synthases
  • Open Reading Frames
  • Molecular Sequence Data
  • L-Aminoadipate-Semialdehyde Dehydrogenase
  • Genes, Fungal
  • Genes, Bacterial
  • Developmental Biology
 

Citation

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Morris, M. E., & Jinks-Robertson, S. (1991). Nucleotide sequence of the LYS2 gene of Saccharomyces cerevisiae: homology to Bacillus brevis tyrocidine synthetase 1. Gene, 98(1), 141–145. https://doi.org/10.1016/0378-1119(91)90117-t
Morris, M. E., and S. Jinks-Robertson. “Nucleotide sequence of the LYS2 gene of Saccharomyces cerevisiae: homology to Bacillus brevis tyrocidine synthetase 1.Gene 98, no. 1 (February 1, 1991): 141–45. https://doi.org/10.1016/0378-1119(91)90117-t.
Morris, M. E., and S. Jinks-Robertson. “Nucleotide sequence of the LYS2 gene of Saccharomyces cerevisiae: homology to Bacillus brevis tyrocidine synthetase 1.Gene, vol. 98, no. 1, Feb. 1991, pp. 141–45. Pubmed, doi:10.1016/0378-1119(91)90117-t.
Journal cover image

Published In

Gene

DOI

ISSN

0378-1119

Publication Date

February 1, 1991

Volume

98

Issue

1

Start / End Page

141 / 145

Location

Netherlands

Related Subject Headings

  • Sequence Homology, Nucleic Acid
  • Saccharomyces cerevisiae
  • Restriction Mapping
  • Peptide Synthases
  • Open Reading Frames
  • Molecular Sequence Data
  • L-Aminoadipate-Semialdehyde Dehydrogenase
  • Genes, Fungal
  • Genes, Bacterial
  • Developmental Biology