Calibrating the bootstrap test of monophyly.


Journal Article

It has been suggested that the bootstrap test of monophyly is too conservative, i.e. the test rejects the hypothesis of monophyly when it is true far too often. Here, a method called the iterated bootstrap is described which estimates by randomization the probabilities associated with rejecting the hypothesis of monophyly when it is true and accepting the hypothesis of monophyly when it is false. Using this method, the bootstrap test can be calibrated by taking account of the errors associated with the hypothesis test. This method is applied to the high-level phylogeny of the Platyhelminthes using 18S rRNA sequences. The analysis suggests that the data cannot unequivocally resolve the placement of the Platyhelminthes with respect to the Annelida and Insecta.

Full Text

Cited Authors

  • Rodrigo, AG

Published Date

  • July 1993

Published In

Volume / Issue

  • 23 / 4

Start / End Page

  • 507 - 514

PubMed ID

  • 8354601

Pubmed Central ID

  • 8354601

Electronic International Standard Serial Number (EISSN)

  • 1879-0135

International Standard Serial Number (ISSN)

  • 0020-7519

Digital Object Identifier (DOI)

  • 10.1016/0020-7519(93)90040-6


  • eng