Effect of age on outcomes after left ventricular assist device placement.

Journal Article (Journal Article)

The influence of age on outcomes after left ventricular assist device (LVAD) implantation is not well studied. To address this question, we assessed 222 patients who underwent LVAD placement and were divided into quartiles based on age (years): group 1, or=60. Eighty-four patients died on LVAD support. Six- and 12-month survivals for the four groups of LVAD patients were 67.7, 73.7, 49.8, and 38.2, and 49.4, 57.3, 42.7, and 26.2, respectively (all P<.01). Older patients showed a higher risk of infections, embolic strokes, and respiratory complications. They were the least likely to undergo reoperations postimplantation (56%, 53%, 50%, 46%, P=.06). After adjusting for baseline differences between the groups, there was a trend toward increasing mortality with age, which did not reach significance (odds ratio 1.93; 95% confidence interval 0.95 to 3.92 for the oldest quartile as compared with the youngest). In conclusion, these results suggest in the absence of other high risk factors, age alone should not be used as an independent contraindication for LVAD implantation.

Full Text

Duke Authors

Cited Authors

  • Huang, R; Deng, M; Rogers, JG; Howser, R; Portner, PM; Pierson, RN; Butler, J

Published Date

  • June 2006

Published In

Volume / Issue

  • 38 / 5

Start / End Page

  • 1496 - 1498

PubMed ID

  • 16797341

International Standard Serial Number (ISSN)

  • 0041-1345

Digital Object Identifier (DOI)

  • 10.1016/j.transproceed.2006.02.115


  • eng

Conference Location

  • United States