Acute eosinophilic pneumonia in a New York City firefighter exposed to World Trade Center dust.

Journal Article (Journal Article)

We report a sentinel case of acute eosinophilic pneumonia in a firefighter exposed to high concentrations of World Trade Center dust during the rescue effort from September 11 to 24. The firefighter presented with a Pa(O2) of 53 mm Hg and responded to oxygen and corticosteroids. Computed tomography scan showed patchy ground glass density, thickened bronchial walls, and bilateral pleural effusions. Bronchoalveolar lavage recovered 70% eosinophils, with only 1% eosinophils in peripheral blood. Eosinophils were not degranulated and increased levels of interleukin-5 were measured in bronchoalveolar lavage and serum. Mineralogic analysis counted 305 commercial asbestos fibers/10(6) macrophages including those with high aspect ratios, and significant quantities of fly ash and degraded fibrous glass. Acute eosinophilic pneumonia is a rare consequence of acute high dust exposure. World Trade Center dust consists of large particle-size silicates, but fly ash and asbestos fibers may be found in bronchoalveolar lavage cells.

Full Text

Duke Authors

Cited Authors

  • Rom, WN; Weiden, M; Garcia, R; Yie, TA; Vathesatogkit, P; Tse, DB; McGuinness, G; Roggli, V; Prezant, D

Published Date

  • September 15, 2002

Published In

Volume / Issue

  • 166 / 6

Start / End Page

  • 797 - 800

PubMed ID

  • 12231487

International Standard Serial Number (ISSN)

  • 1073-449X

Digital Object Identifier (DOI)

  • 10.1164/rccm.200206-576OC


  • eng

Conference Location

  • United States