Fluoxetine in post-traumatic stress disorder

Journal Article (Journal Article)

Fluoxetine was given to five nonveteran patients with post-traumatic stress disorder (PTSD). The maximum doses ranged from 20 to 80 mg/day, and treatment was continued for between 8 and 32 weeks. In contrast to published reports of other drugs, which were noted to improve only the intrusive symptoms of PTSD, fluoxetine was associated with marked improvement of both intrusive and avoidant symptoms. Facilitative effects of fluoxetine were noted on trauma-focused psychotherapy in two adult victims of childhood sexual trauma. In part, these effects were related to modulating effects of the drug upon the intensity of core PTSD symptoms. Serotonergic drugs appear to hold promise for the treatment of PTSD. © 1991 Plenum Publishing Corporation.

Full Text

Duke Authors

Cited Authors

  • Davidson, J; Roth, S; Newman, E

Published Date

  • July 1, 1991

Published In

Volume / Issue

  • 4 / 3

Start / End Page

  • 419 - 423

Electronic International Standard Serial Number (EISSN)

  • 1573-6598

International Standard Serial Number (ISSN)

  • 0894-9867

Digital Object Identifier (DOI)

  • 10.1007/BF00974559

Citation Source

  • Scopus