Prophylaxis with isoniazid for low-risk tuberculin reactors


Journal Article

We evaluated the effectiveness and costs by giving monitored prophylaxis to low-risk tuberculin reactors aged 35, 50, or 70 years. Compared with no prophylaxis, we found that isoniazid prophylaxis increased the probability of survival at 1 year and for all subsequent years. If all low-risk tuberculin reactors over the age of 35 in the United States were given prophylaxis, 35,000 lives could be saved and health expenditures reduced by more than $2 billion.

Duke Authors

Cited Authors

  • Salpeter, SR; Sanders, GD; Truwit, JD

Published Date

  • January 1, 1998

Published In

Volume / Issue

  • 15 / 12

Start / End Page

  • 43 - 47

International Standard Serial Number (ISSN)

  • 1092-6607

Citation Source

  • Scopus