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Botulinum toxin injection into vocal cord in the treatment of malignant coprolalia associated with Tourette's syndrome.

Publication ,  Journal Article
Scott, BL; Jankovic, J; Donovan, DT
Published in: Mov Disord
July 1996

We describe a 13-year-old boy with Tourette's syndrome (TS) manifested chiefly by severe coprolalia, obsessive compulsive disorder, and attention deficit hyperactivity disorder. He was treated with unilateral injections of botulinum toxin to the vocal cord and experienced marked improvement in coprolalia as well as marked reduction in the premonitory urges associated with the vocal tics and coprolalia. As a result of the improvement, the patient was able to attend school and church and was able to socialize. Botulinum toxin may interfere with a sensory reflex arc required to perpetuate tics and coprolalia in TS, possibly by reducing local build-up of tension or muscle contraction in affected areas.

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Published In

Mov Disord

DOI

ISSN

0885-3185

Publication Date

July 1996

Volume

11

Issue

4

Start / End Page

431 / 433

Location

United States

Related Subject Headings

  • Vocal Cords
  • Verbal Behavior
  • Treatment Outcome
  • Tourette Syndrome
  • Neurology & Neurosurgery
  • Male
  • Injections, Intramuscular
  • Humans
  • Botulinum Toxins
  • Adolescent
 

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Scott, B. L., Jankovic, J., & Donovan, D. T. (1996). Botulinum toxin injection into vocal cord in the treatment of malignant coprolalia associated with Tourette's syndrome. Mov Disord, 11(4), 431–433. https://doi.org/10.1002/mds.870110413
Scott, B. L., J. Jankovic, and D. T. Donovan. “Botulinum toxin injection into vocal cord in the treatment of malignant coprolalia associated with Tourette's syndrome.Mov Disord 11, no. 4 (July 1996): 431–33. https://doi.org/10.1002/mds.870110413.
Scott, B. L., et al. “Botulinum toxin injection into vocal cord in the treatment of malignant coprolalia associated with Tourette's syndrome.Mov Disord, vol. 11, no. 4, July 1996, pp. 431–33. Pubmed, doi:10.1002/mds.870110413.
Journal cover image

Published In

Mov Disord

DOI

ISSN

0885-3185

Publication Date

July 1996

Volume

11

Issue

4

Start / End Page

431 / 433

Location

United States

Related Subject Headings

  • Vocal Cords
  • Verbal Behavior
  • Treatment Outcome
  • Tourette Syndrome
  • Neurology & Neurosurgery
  • Male
  • Injections, Intramuscular
  • Humans
  • Botulinum Toxins
  • Adolescent