RCT of a psychological intervention for patients with cancer: I. mechanisms of change.


Journal Article

Little is known about the therapeutic processes contributing to efficacy of psychological interventions for patients with cancer. Data from a randomized clinical trial yielding robust biobehavioral and health effects (B. L. Andersen et al., 2004, 2007) were used to examine associations between process variables, treatment utilization, and outcomes. Novel findings emerged. Patients were highly satisfied with the treatment, but their higher levels of felt support (group cohesion) covaried with lower distress and fewer symptoms. Also, specific treatment strategies were associated with specific outcomes, including lower distress, improved dietary habits, reduced symptomatology, and higher chemotherapy dose intensity. These data provide a comprehensive test of multiple therapeutic processes and mechanisms for biobehavioral change with an intervention including both intensive and maintenance phases.

Full Text

Duke Authors

Cited Authors

  • Andersen, BL; Shelby, RA; Golden-Kreutz, DM

Published Date

  • December 2007

Published In

Volume / Issue

  • 75 / 6

Start / End Page

  • 927 - 938

PubMed ID

  • 18085909

Pubmed Central ID

  • 18085909

International Standard Serial Number (ISSN)

  • 0022-006X

Digital Object Identifier (DOI)

  • 10.1037/0022-006X.75.6.927


  • eng

Conference Location

  • United States