Regulation of ion transport by the NHERF family of PDZ proteins.

Journal Article (Journal Article;Review)

NHERFs are the best-studied apical PDZ proteins that are highly expressed in epithelial cells. Molecular and cellular studies over the past decade show that NHERFs regulate the targeting or trafficking of ion transporters and other membrane proteins and transduce physiological and pathophysiological signals that regulate ion homeostasis in mammals.

Full Text

Duke Authors

Cited Authors

  • Shenolikar, S; Voltz, JW; Cunningham, R; Weinman, EJ

Published Date

  • December 2004

Published In

Volume / Issue

  • 19 /

Start / End Page

  • 362 - 369

PubMed ID

  • 15546854

Pubmed Central ID

  • 15546854

International Standard Serial Number (ISSN)

  • 1548-9213

Digital Object Identifier (DOI)

  • 10.1152/physiol.00020.2004


  • eng

Conference Location

  • United States