Reperfusion and compartment syndromes: strategies for prevention and treatment.

Journal Article (Journal Article;Review)

Reperfusion syndrome refers to the damage done by restoration of blood flow to ischemic tissues and is distinct from the original ischemic insult itself, whereas compartment syndrome refers to the damage resulting from increased pressure within an enclosed fascial compartment that occurs after blood flow has been restored. Despite extensive experimental work directed toward the treatment of established reperfusion injury and prevention of compartment syndrome, clinical outcome over the past decade has not appreciably changed. Although the systemic insult, thought to be an inevitable result of reperfusion injury, may be less injurious than "conventional wisdom" would suggest, no better strategy for treating compartment syndrome other than early recognition and decompression has yet been developed.

Full Text

Duke Authors

Cited Authors

  • Lyden, SP; Shortell, CK; Illig, KA

Published Date

  • June 2001

Published In

Volume / Issue

  • 14 / 2

Start / End Page

  • 107 - 113

PubMed ID

  • 11400086

International Standard Serial Number (ISSN)

  • 0895-7967

Digital Object Identifier (DOI)

  • 10.1053/svas.2001.23166


  • eng

Conference Location

  • United States