Prospective evaluation of pulmonary artery pressures during pulmonary angiography performed with low-osmolar nonionic contrast media.
Journal Article (Clinical Trial;Journal Article)
PURPOSE: To determine the effects of pulmonary angiography performed with low-osmolar, nonionic contrast media on pulmonary artery pressures. PATIENTS AND METHODS: In a prospective, uncontrolled clinical trial, pulmonary artery pressures (systolic, diastolic, mean) of 116 patients referred for pulmonary angiography were recorded before and 1 and 5 minutes after injection of contrast material. RESULTS: There was a statistically significant rise in systolic, diastolic, and mean pulmonary artery pressure at 1 minute (4.6, 3.4, 4.1 mm Hg, respectively) and 5 minutes (3.8, 2.7, 3.4 mm Hg, respectively) after the initial contrast material injection (P < .05). Increases were smaller with additional injections. Systolic pressure changes at 1 and 5 minutes after the first injection were linearly dependent on the volume of contrast material injected (P < .05). There was no statistically significant difference in the increase in pulmonary artery pressure between patients with pulmonary embolus or pulmonary arterial hypertension and those without. CONCLUSION: There is a small but statistically significant rise in pulmonary artery pressure after injection of low-osmolar, nonionic contrast material for pulmonary angiography; it is unlikely to be of clinical significance.
Full Text
Duke Authors
Cited Authors
- Smith, TP; Lee, VS; Hudson, ER; Newman, GE; Payne, CS; Suhocki, PV; McDermott, VG; Stackhouse, DJ
Published Date
- 1996
Published In
Volume / Issue
- 7 / 2
Start / End Page
- 207 - 212
PubMed ID
- 9007799
International Standard Serial Number (ISSN)
- 1051-0443
Digital Object Identifier (DOI)
- 10.1016/s1051-0443(96)70763-7
Language
- eng
Conference Location
- United States