Grab your partner with both hands: cytoskeletal remodeling by Arp2/3 signaling.
Publication
, Journal Article
Soderling, SH
Published in: Sci Signal
January 27, 2009
The seemingly simple structure of the actin filament belies the elaborate signaling pathways that regulate its assembly and disassembly in eukaryotic cells. In retrospect, this signaling complexity should not be surprising. Actin regulates many dynamic cellular processes, including protein and organelle trafficking, establishment of cell polarity, directional migration, cellular traction, and the efficiency of endocytosis. Signaling events that coordinately control actin turnover during these processes must display a high degree of sophistication. Emerging data on an important regulator of actin dynamics, the actin-related protein 2 and 3 (Arp2/3) complex, suggest a model of how this may occur.
Duke Scholars
Published In
Sci Signal
DOI
EISSN
1937-9145
Publication Date
January 27, 2009
Volume
2
Issue
55
Start / End Page
pe5
Location
United States
Related Subject Headings
- Signal Transduction
- Protein Structure, Tertiary
- Neurons
- Models, Biological
- Cytoskeleton
- Cell Polarity
- Cell Movement
- Animals
- Actins
- Actin-Related Protein 2-3 Complex
Citation
APA
Chicago
ICMJE
MLA
NLM
Soderling, S. H. (2009). Grab your partner with both hands: cytoskeletal remodeling by Arp2/3 signaling. Sci Signal, 2(55), pe5. https://doi.org/10.1126/scisignal.255pe5
Soderling, Scott H. “Grab your partner with both hands: cytoskeletal remodeling by Arp2/3 signaling.” Sci Signal 2, no. 55 (January 27, 2009): pe5. https://doi.org/10.1126/scisignal.255pe5.
Soderling SH. Grab your partner with both hands: cytoskeletal remodeling by Arp2/3 signaling. Sci Signal. 2009 Jan 27;2(55):pe5.
Soderling, Scott H. “Grab your partner with both hands: cytoskeletal remodeling by Arp2/3 signaling.” Sci Signal, vol. 2, no. 55, Jan. 2009, p. pe5. Pubmed, doi:10.1126/scisignal.255pe5.
Soderling SH. Grab your partner with both hands: cytoskeletal remodeling by Arp2/3 signaling. Sci Signal. 2009 Jan 27;2(55):pe5.
Published In
Sci Signal
DOI
EISSN
1937-9145
Publication Date
January 27, 2009
Volume
2
Issue
55
Start / End Page
pe5
Location
United States
Related Subject Headings
- Signal Transduction
- Protein Structure, Tertiary
- Neurons
- Models, Biological
- Cytoskeleton
- Cell Polarity
- Cell Movement
- Animals
- Actins
- Actin-Related Protein 2-3 Complex