Overshoot of oxygen pressure in post-hypoxic brain tissue: a re-evaluation.
Published
Journal Article
Tissue oxygen pressure (ptO2) was measured with noble metal microelectrodes in hippocampal slices in vitro. During hypoxia, the ptO2 at 100 micron depth fell rapidly to less than 20 mm Hg. During reoxygenation, large transient ptO2 increases above normoxic values were observed. These data demonstrate that ptO2 'overshoots' occur independently of in situ posthypoxic hyperemia and may reflect pathologic chemical reactions in brain tissue during reoxygenation.
Full Text
Duke Authors
Cited Authors
- Schiff, SJ; Somjen, GG
Published Date
- September 30, 1985
Published In
Volume / Issue
- 344 / 1
Start / End Page
- 150 - 153
PubMed ID
- 4041862
Pubmed Central ID
- 4041862
International Standard Serial Number (ISSN)
- 0006-8993
Digital Object Identifier (DOI)
- 10.1016/0006-8993(85)91200-4
Language
- eng
Conference Location
- Netherlands