Frontal eye field neurons orthodromically activated from the superior colliculus.
Journal Article (Journal Article)
Frontal eye field neurons orthodromically activated from the superior colliculus. J. Neurophysiol. 80: 3331-3333, 1998. Anatomical studies have shown that the frontal eye field (FEF) and superior colliculus (SC) of monkeys are reciprocally connected, and a physiological study described the signals sent from the FEF to the SC. Nothing is known, however, about the signals sent from the SC to the FEF. We physiologically identified and characterized FEF neurons that are likely to receive input from the SC. Fifty-two FEF neurons were found that were orthodromically activated by electrical stimulation of the intermediate or deeper layers of the SC. All the neurons that we tested (n = 34) discharged in response to visual stimulation. One-half also discharged when saccadic eye movements were made. This provides the first direct evidence that the ascending pathway from SC to FEF might carry visual- and saccade-related signals. Our findings support a hypothesis that the SC and the FEF interact bidirectionally during the events leading up to saccade generation.
Full Text
Duke Authors
Cited Authors
- Sommer, MA; Wurtz, RH
Published Date
- December 1998
Published In
Volume / Issue
- 80 / 6
Start / End Page
- 3331 - 3335
PubMed ID
- 9862927
Pubmed Central ID
- 9862927
Electronic International Standard Serial Number (EISSN)
- 1522-1598
International Standard Serial Number (ISSN)
- 0022-3077
Digital Object Identifier (DOI)
- 10.1152/jn.1998.80.6.3331
Language
- eng