New neuroblast markers and the origin of the aCC/pCC neurons in the Drosophila central nervous system.

Journal Article (Journal Article)

Drosophila is an ideal system for identifying genes that control central nervous system (CNS) development. Particularly useful tools include molecular markers for subsets of neural precursors (neuroblasts) and the simple expression pattern of the even-skipped (eve) gene in a subset of neurons. Here we provide additional molecular markers for identified neuroblasts, including several with near single cell specificity. In addition, we use these new markers to trace the development of several eve+ neurons. Our results shows that the eve+ aCC/pCC neurons develop from a different neuroblast than previously thought, and have led us to assign new names for several neuroblasts. These results are supported by DiI cell lineage analysis of neuroblasts identified in vivo.

Full Text

Duke Authors

Cited Authors

  • Broadus, J; Skeath, JB; Spana, EP; Bossing, T; Technau, G; Doe, CQ

Published Date

  • November 1995

Published In

Volume / Issue

  • 53 / 3

Start / End Page

  • 393 - 402

PubMed ID

  • 8645605

Electronic International Standard Serial Number (EISSN)

  • 1872-6356

International Standard Serial Number (ISSN)

  • 0925-4773

Digital Object Identifier (DOI)

  • 10.1016/0925-4773(95)00454-8


  • eng