Prox 1, a prospero-related homeobox gene expressed during mouse development.
Publication
, Journal Article
Oliver, G; Sosa-Pineda, B; Geisendorf, S; Spana, EP; Doe, CQ; Gruss, P
Published in: Mechanisms of development
November 1993
Prox 1, a likely mouse homologue of the Drosophila homeobox gene prospero has been cloned and its expression pattern analyzed during development. In Drosophila, prospero is expressed in the developing CNS, lens-secreting cone cells of the eye, and midgut. In the mouse, Prox 1 is expressed in many of the same tissues: young neurons of the subventricular region of the CNS, developing eye lens and pancreas. Expression is also detected in the developing liver and heart, as well as transiently in the skeletal muscles. The similarities in protein sequence and expression patterns between the mouse and fly cognate genes suggest that Prox 1 may play, among others, a fundamental role in early development of the murine CNS.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Mechanisms of development
DOI
EISSN
1872-6356
ISSN
0925-4773
Publication Date
November 1993
Volume
44
Issue
1
Start / End Page
3 / 16
Related Subject Headings
- Pancreas
- Molecular Sequence Data
- Mice
- Liver
- Genes, Homeobox
- Gene Expression
- Eye
- Embryonic and Fetal Development
- Developmental Biology
- Cloning, Molecular
Citation
APA
Chicago
ICMJE
MLA
NLM
Oliver, G., Sosa-Pineda, B., Geisendorf, S., Spana, E. P., Doe, C. Q., & Gruss, P. (1993). Prox 1, a prospero-related homeobox gene expressed during mouse development. Mechanisms of Development, 44(1), 3–16. https://doi.org/10.1016/0925-4773(93)90012-m
Oliver, G., B. Sosa-Pineda, S. Geisendorf, E. P. Spana, C. Q. Doe, and P. Gruss. “Prox 1, a prospero-related homeobox gene expressed during mouse development.” Mechanisms of Development 44, no. 1 (November 1993): 3–16. https://doi.org/10.1016/0925-4773(93)90012-m.
Oliver G, Sosa-Pineda B, Geisendorf S, Spana EP, Doe CQ, Gruss P. Prox 1, a prospero-related homeobox gene expressed during mouse development. Mechanisms of development. 1993 Nov;44(1):3–16.
Oliver, G., et al. “Prox 1, a prospero-related homeobox gene expressed during mouse development.” Mechanisms of Development, vol. 44, no. 1, Nov. 1993, pp. 3–16. Epmc, doi:10.1016/0925-4773(93)90012-m.
Oliver G, Sosa-Pineda B, Geisendorf S, Spana EP, Doe CQ, Gruss P. Prox 1, a prospero-related homeobox gene expressed during mouse development. Mechanisms of development. 1993 Nov;44(1):3–16.
Published In
Mechanisms of development
DOI
EISSN
1872-6356
ISSN
0925-4773
Publication Date
November 1993
Volume
44
Issue
1
Start / End Page
3 / 16
Related Subject Headings
- Pancreas
- Molecular Sequence Data
- Mice
- Liver
- Genes, Homeobox
- Gene Expression
- Eye
- Embryonic and Fetal Development
- Developmental Biology
- Cloning, Molecular