Isolation and characterization of the Haemophilus influenzae uvrA gene.


Journal Article

The uvrA gene Haemophilus influenzae (Hi) was cloned and sequenced. Analysis of the deduced amino acid sequence revealed 81% identity and 90% similarity with the Escherichia coli UvrA protein. Consistent with a role of Hi uvrA in DNA repair, a Hi uvrA mutant exhibited increased sensitivity of UV irradiation. Furthermore, Hi uvrA was able to complement a mutation in the E. coli uvrA locus.

Full Text

Cited Authors

  • de la Morena, ML; Hendrixson, DR; St Geme, JW

Published Date

  • October 1996

Published In

Volume / Issue

  • 177 / 1-2

Start / End Page

  • 23 - 28

PubMed ID

  • 8921840

Pubmed Central ID

  • 8921840

Electronic International Standard Serial Number (EISSN)

  • 1879-0038

International Standard Serial Number (ISSN)

  • 0378-1119

Digital Object Identifier (DOI)

  • 10.1016/0378-1119(96)00264-8


  • eng