Psychosis and Parkinson's disease

Journal Article (Journal Article)

Parkinson's disease (PD) psychosis is a common phenomenon that affects quality of life, caregiver burden, and disability in patients with PD. Although there may be an increased risk of psychosis inherent to the disease itself, current research suggests that dementia, advancing age, and concomitant medication use increase the risk of psychosis in PD. Symptoms of psychosis in this population may include hallucinations, delusions, paranoia, false sense of presence, and illusions. Early intervention may be important for delaying progression of psychotic symptoms. Treatment options for PD-related psychosis include reduction of dopaminergic therapy, switch to levodopa, simplification of polypharmacy and addition of an atypical antipsychotic, such as quetiapine and clozapine. Copyright © 2012 S. Karger AG, Basel.

Full Text

Duke Authors

Cited Authors

  • Jakel, RJ; Stacy, MA

Published Date

  • December 4, 2012

Published In

Volume / Issue

  • 27 /

Start / End Page

  • 53 - 60

Electronic International Standard Serial Number (EISSN)

  • 1662-2774

International Standard Serial Number (ISSN)

  • 0378-7354

Digital Object Identifier (DOI)

  • 10.1159/000331526

Citation Source

  • Scopus