A cohort analysis of U.S. stomach cancer mortality 1950-1977.
Journal Article (Journal Article)
Models of human carcinogenesis, such as the multi-stage model of Armitage and Doll, are designed to explain the age increase in the incidence of cancers in individuals. As a consequence, analyses of population level age-specific death rates via such models are appropriately applied to cohort data where such data are available. In this study a multi-stage model is applied to cohort data for stomach cancer death rates in the U.S. population for nine distinct cohorts observed over a recent 28-year period (1950-1977). The multi-stage model parameters obtained from the analysis of the cohort data show significant differences from the parameters obtained from analyses of cross-sectional mortality data under the assumption of no cohort differences in age-specific stomach cancer death rates.
Full Text
Duke Authors
Cited Authors
- Manton, KG; Stallard, E
Published Date
- March 1982
Published In
Volume / Issue
- 11 / 1
Start / End Page
- 49 - 61
PubMed ID
- 7085178
Electronic International Standard Serial Number (EISSN)
- 1464-3685
International Standard Serial Number (ISSN)
- 0300-5771
Digital Object Identifier (DOI)
- 10.1093/ije/11.1.49
Language
- eng