A cohort analysis of U.S. stomach cancer mortality 1950-1977.

Journal Article (Journal Article)

Models of human carcinogenesis, such as the multi-stage model of Armitage and Doll, are designed to explain the age increase in the incidence of cancers in individuals. As a consequence, analyses of population level age-specific death rates via such models are appropriately applied to cohort data where such data are available. In this study a multi-stage model is applied to cohort data for stomach cancer death rates in the U.S. population for nine distinct cohorts observed over a recent 28-year period (1950-1977). The multi-stage model parameters obtained from the analysis of the cohort data show significant differences from the parameters obtained from analyses of cross-sectional mortality data under the assumption of no cohort differences in age-specific stomach cancer death rates.

Full Text

Duke Authors

Cited Authors

  • Manton, KG; Stallard, E

Published Date

  • March 1982

Published In

Volume / Issue

  • 11 / 1

Start / End Page

  • 49 - 61

PubMed ID

  • 7085178

Electronic International Standard Serial Number (EISSN)

  • 1464-3685

International Standard Serial Number (ISSN)

  • 0300-5771

Digital Object Identifier (DOI)

  • 10.1093/ije/11.1.49


  • eng