A dynamic analysis of chronic disease development: a study of sex specific changes in coronary heart disease incidence and risk factors in Framingham.

Journal Article (Journal Article)

An analysis of sex differentials in the dynamics of coronary heart disease (CHD) in the Framingham study is conducted using a methodology designed process which aids in the interpretation of the longitudinal results. This methodology permits the analysis of risk variable changes over time to be conducted independently of the analysis of the relation of risk variable values to CHD risk. The independent analyses afford a complete utilisation of information from longitudinal studies of chronic disease risk and produce insights into the dynamics of chronic disease development not available by other analytic strategies. The results of this analysis are compared with results obtained from a similarly structured multiple logistic analysis--a comparison which illustrates some of the technical and conceptual deficiencies of the often employed multiple logistic analysis when applied to longitudinal data.

Full Text

Duke Authors

Cited Authors

  • Woodbury, MA; Manton, KG; Stallard, E

Published Date

  • December 1, 1981

Published In

Volume / Issue

  • 10 / 4

Start / End Page

  • 355 - 366

PubMed ID

  • 7327834

Electronic International Standard Serial Number (EISSN)

  • 1464-3685

International Standard Serial Number (ISSN)

  • 0300-5771

Digital Object Identifier (DOI)

  • 10.1093/ije/10.4.355


  • eng