Long-term implantation of voltammetric oxidase/peroxide glucose sensors in the rat peritoneum.

Journal Article

Methods for designing, fabricating, testing in vitro and in vivo, and improving chronically implantable oxidase/peroxide-type polarographic glucose sensors are described. Voltammetric means to evaluate oxygen supply to the sensor and to measure the nearby microcirculation with hydrogen washout techniques using the implanted glucose sensor are outlined. Because some peritoneally implanted sensors have, perhaps surprisingly, remained functional for months, such devices may prove with further development to be useful as the sensing components in artificial pancreatic beta cells for the control of diabetes.

Full Text

Duke Authors

Cited Authors

  • Clark, LC; Noyes, LK; Spokane, RB; Sudan, R; Miller, ML

Published Date

  • 1988

Published In

Volume / Issue

  • 137 /

Start / End Page

  • 68 - 89

PubMed ID

  • 3374363

International Standard Serial Number (ISSN)

  • 0076-6879

Language

  • eng

Conference Location

  • United States