Long-term implantation of voltammetric oxidase/peroxide glucose sensors in the rat peritoneum.
Journal Article (Journal Article)
Methods for designing, fabricating, testing in vitro and in vivo, and improving chronically implantable oxidase/peroxide-type polarographic glucose sensors are described. Voltammetric means to evaluate oxygen supply to the sensor and to measure the nearby microcirculation with hydrogen washout techniques using the implanted glucose sensor are outlined. Because some peritoneally implanted sensors have, perhaps surprisingly, remained functional for months, such devices may prove with further development to be useful as the sensing components in artificial pancreatic beta cells for the control of diabetes.
Full Text
Duke Authors
Cited Authors
- Clark, LC; Noyes, LK; Spokane, RB; Sudan, R; Miller, ML
Published Date
- 1988
Published In
Volume / Issue
- 137 /
Start / End Page
- 68 - 89
PubMed ID
- 3374363
International Standard Serial Number (ISSN)
- 0076-6879
Digital Object Identifier (DOI)
- 10.1016/0076-6879(88)37008-4
Language
- eng
Conference Location
- United States