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Suppression of hippocampal epileptiform activity in vitro after laser exposure

Publication ,  Journal Article
Walker, JB; Swartzwelder, HS; Bondy, SC
Published in: LASER THERAPY
January 1, 1989

Extracellular field potentials were recorded in stratum pyramidate of CA3 in hippocampal slices prepared from male Sprague-Dawley rats. Electrical stimuli were delivered lo s. radiatum of CA3. After stable responses were established, stimulus trains were delivered every 5min until stable triggered and spontaneous population bursts were elicited. The slices were then irradiated with a low power (25 mW) argon laser. No changes in the morphology or number of epileptiform bursts were found while the laser was on. However, when the laser was turned eff. there was a highly significant reduction in frequency and morphology of bursts, These results indicate that exposure to light alters epileptiform activity within the hippocampus in vitro, and provides evidence indicating that the central nervous system is photosensitive. © 1989, International Phototherapy Association. All rights reserved.

Duke Scholars

Published In

LASER THERAPY

DOI

EISSN

1884-7269

ISSN

0898-5901

Publication Date

January 1, 1989

Volume

1

Issue

1

Start / End Page

19 / 21
 

Citation

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Walker, J. B., Swartzwelder, H. S., & Bondy, S. C. (1989). Suppression of hippocampal epileptiform activity in vitro after laser exposure. LASER THERAPY, 1(1), 19–21. https://doi.org/10.5978/islsm.89-OR-01
Walker, J. B., H. S. Swartzwelder, and S. C. Bondy. “Suppression of hippocampal epileptiform activity in vitro after laser exposure.” LASER THERAPY 1, no. 1 (January 1, 1989): 19–21. https://doi.org/10.5978/islsm.89-OR-01.
Walker JB, Swartzwelder HS, Bondy SC. Suppression of hippocampal epileptiform activity in vitro after laser exposure. LASER THERAPY. 1989 Jan 1;1(1):19–21.
Walker, J. B., et al. “Suppression of hippocampal epileptiform activity in vitro after laser exposure.” LASER THERAPY, vol. 1, no. 1, Jan. 1989, pp. 19–21. Scopus, doi:10.5978/islsm.89-OR-01.
Walker JB, Swartzwelder HS, Bondy SC. Suppression of hippocampal epileptiform activity in vitro after laser exposure. LASER THERAPY. 1989 Jan 1;1(1):19–21.

Published In

LASER THERAPY

DOI

EISSN

1884-7269

ISSN

0898-5901

Publication Date

January 1, 1989

Volume

1

Issue

1

Start / End Page

19 / 21